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In England, access to Wegovy on the NHS is typically through specialist tier 3 or 4 weight management services, in line with NICE guidance (TA875)

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Tirzepatide offers a non-surgical weight loss alternative, providing a gradual and sustainable approach without the risks and recovery time associated with bariatric surgery

Serotypes such as AAV1, AAV6, AAV8, and especially AAV9 have demonstrated efficient cardiac transduction in small and large animals, enabling robust gene transfer to myocardium with intracoronary or intravenous delivery (Mazurek et al., 2024)

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